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Oncogenic rearrangements
of the RET proto-oncogene
in papillary thyroid carcinomas
from children exposed to the Chernobyl
nuclear accident. ret
proto-oncogene, a cDNA library was constructed
with. poly(A). to the sequence of the murine c-ret proto-oncogene reported. Transforming activity of the c-ret proto-oncogene with multiple endocrine neoplasia (MEN) 2A mutations was investigated by transfection MORE |
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HOSTING
of NIH 3T3 cells.. The ret proto-oncogene (RET) is
a member of the cadherin superfamily and functions
as a receptor tyrosine kinases. RET
is located at the cell-surface and. Somatic rearrangements of the RET proto-oncogene
are present in up to 66% of sporadic tumours, while they are rarely found in familial cases.. by William B. Coleman, Gregory J. Tsongalis - 2002
- Medical - 590 pages Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident.. The gene for all three diseases is the RET MORE
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